GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs11622475 | 1 | rs10136440 | chr14:104397367 | TDRD9 | chr14:104394817-104519002:+ | -0.35 | -5.51 | 6.46E-8 | Bipolar disorder |
| BLCA | cis | rs2239557 | 1 | rs10140433 | chr14:74659989 | LIN52 | chr14:74551656-74667117:+ | -0.36 | -8.09 | 7.85E-15 | Common traits (Other) |
| BLCA | cis | rs2239557 | 1 | rs10144220 | chr14:74647904 | LIN52 | chr14:74551656-74667117:+ | -0.36 | -8.28 | 2.14E-15 | Common traits (Other) |
| BLCA | cis | rs11622475 | 1 | rs10149651 | chr14:104394440 | TDRD9 | chr14:104394817-104519002:+ | -0.34 | -5.49 | 7.41E-8 | Bipolar disorder |
| BLCA | cis | rs2239557 | 1 | rs10150201 | chr14:74649157 | LIN52 | chr14:74551656-74667117:+ | -0.36 | -8.28 | 2.07E-15 | Common traits (Other) |
| BLCA | cis | rs4660306 | 1 | rs10157597 | chr1:45990278 | CCDC163P | chr1:45960581-45965646:- | -0.79 | -16.19 | 2.68E-45 | Homocysteine levels |
| BLCA | cis | rs9815354 | 1 | rs1016669 | chr3:41894440 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.91 | 9.53E-21 | Diastolic blood pressure |
| BLCA | cis | rs9309473 | 1 | rs10169714 | chr2:73808773 | ALMS1P | chr2:73872046-73912692:+ | 0.36 | 5.35 | 1.55E-7 | Metabolite levels |
| BLCA | cis | rs9309473 | 1 | rs10175180 | chr2:73673123 | ALMS1P | chr2:73872046-73912692:+ | 0.39 | 5.82 | 1.23E-8 | Metabolite levels |
| BLCA | cis | rs10178409 | 1 | rs10178409 | chr2:73855507 | ALMS1P | chr2:73872046-73912692:+ | 0.35 | 5.06 | 6.59E-7 | Urinary metabolites |
| BLCA | cis | rs9309473 | 1 | rs10179134 | chr2:73637519 | ALMS1P | chr2:73872046-73912692:+ | 0.33 | 4.84 | 1.89E-6 | Metabolite levels |
| BLCA | cis | rs1577917 | 1 | rs1018184 | chr6:86648475 | SNHG5 | chr6:86386726-86388451:- | 0.49 | 8.81 | 4.4E-17 | Response to antipsychotic treatment |
| BLCA | cis | rs9309473 | 1 | rs10184268 | chr2:73627044 | ALMS1P | chr2:73872046-73912692:+ | 0.35 | 5.19 | 3.51E-7 | Metabolite levels |
| BLCA | cis | rs9309473 | 1 | rs10186501 | chr2:73697844 | ALMS1P | chr2:73872046-73912692:+ | 0.4 | 5.97 | 5.57E-9 | Metabolite levels |
| BLCA | cis | rs9309473 | 1 | rs10187192 | chr2:73713500 | ALMS1P | chr2:73872046-73912692:+ | 0.33 | 4.75 | 2.87E-6 | Metabolite levels |